Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 4/20 | 0.50 |
| ▸ | AHR | P35869 | 3/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431448 | 1.00 | RHEB (0.50) | RHEBAHRCSNK2A1HTR6MAPT | |
| SCHEMBL1020056 | 0.78 | AHR (0.54) | RHEBAHRCSNK2A1HTR6CYP2A6 | |
| SCHEMBL2080141 | 0.78 | RHEB (0.37) | RHEBAHRHTR6MAPTPRKCI | |
| SCHEMBL29644241 | 0.78 | AHR (0.54) | RHEBAHRCSNK2A1HTR6CYP2A6 | |
| SCHEMBL2516555 | 0.75 | RHEB (0.50) | RHEBAHRCSNK2A1HTR6CYP2A6 | |
| SCHEMBL996179 | 0.75 | AHR (0.50) | RHEBAHRCSNK2A1HTR6CYP2A6 | |
| SCHEMBL915763 | 0.75 | RPS6KA3 (0.40) | AHRHTR6MAPTALDH1A1HPGD | |
| SCHEMBL16620614 | 0.75 | CLK1 (0.36) | RHEBAHRHTR6PRKCIALDH1A1 | |
| SCHEMBL31435859 | 0.75 | RHEB (0.50) | RHEBAHRCSNK2A1CYP2A6NR4A2 | |
| SCHEMBL17369082 | 0.75 | RHEB (0.50) | RHEBAHRCSNK2A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420513-A | Preparation method of 4-bromo-6-aminoindole | 苏州桦冠生物技术有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-118420513-A | Preparation method of 4-bromo-6-aminoindole | 苏州桦冠生物技术有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-118420513-A | Preparation method of 4-bromo-6-aminoindole | 苏州桦冠生物技术有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-118420513-A | Preparation method of 4-bromo-6-aminoindole | 苏州桦冠生物技术有限公司 | 2024-08-02 | — | — | CN | disclosed |
| WO-2024051784-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 上海璎黎药业有限公司 | 2024-03-14 | — | — | WO | disclosed |