Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30396068 | 1.00 | USP2 (0.44) | USP2SMN1; SMN2CYP11B2USP30RORC | |
| SCHEMBL29002653 | 0.91 | HPGD (0.42) | USP2SMN1; SMN2CYP11B2USP30HPGD | |
| SCHEMBL16635353 | 0.90 | USP2 (0.50) | USP2SMN1; SMN2HPGDEPHX2 | |
| SCHEMBL31343939 | 0.87 | USP2 (0.44) | USP2SMN1; SMN2CYP11B2USP30RORC | |
| SCHEMBL1604637 | 0.87 | USP2 (0.44) | USP2SMN1; SMN2CYP11B2USP30RORC | |
| SCHEMBL31486856 | 0.84 | NR1H2 (0.39) | USP2SMN1; SMN2CYP11B2USP30RORC | |
| SCHEMBL12445300 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2CYP11B2USP30RORC | |
| SCHEMBL31616252 | 0.83 | HPGD (0.41) | USP2SMN1; SMN2CYP11B2USP30RORC | |
| SCHEMBL1061211 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2CYP11B2USP30RORC | |
| SCHEMBL23763417 | 0.82 | USP2 (0.40) | USP2SMN1; SMN2CYP11B2USP30RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024061365-A1 | PYRIMIDINE FUSED RING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 成都奥睿药业有限公司 | 2024-03-28 | — | — | WO | disclosed |