Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10581383 | 0.69 | PARP1 (0.37) | TSHRKMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL29765632 | 0.63 | HPGD (0.59) | POLBKMT2AOPRM1OPRK1OPRL1 | |
| SCHEMBL29712289 | 0.63 | BRD4 (0.50) | TSHRSMN1; SMN2LMNAMAPTCYP2C19 | |
| SCHEMBL29311510 | 0.63 | PARP1 (0.42) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL25723262 | 0.63 | CYP2C19 (0.42) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL9577060 | 0.63 | PARP1 (0.46) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL2614748 | 0.63 | BRD4 (0.50) | TSHRSMN1; SMN2LMNAMAPTCYP2C19 | |
| SCHEMBL3515138 | 0.63 | DAO (0.47) | TSHRKMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL27254155 | 0.63 | PARP1 (0.42) | TSHRSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL11056945 | 0.62 | CDK4 (0.51) | TSHRALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4590396-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | Astrazeneca AB (SE) | 2025-07-30 | — | — | EP | disclosed |
| WO-2024062089-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-03-28 | — | — | WO | disclosed |