Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 20/20 | 0.74 |
| ▸ | AKT2 | P31751 | 16/20 | 0.74 |
| ▸ | AKT3 | Q9Y243 | 15/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27257671 | 1.00 | AKT1 (0.74) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL31455814 | 0.92 | AKT1 (0.82) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL27257669 | 0.91 | AKT1 (0.76) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL30826590 | 0.91 | AKT1 (0.76) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL25386408 | 0.91 | AKT1 (0.71) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL27265230 | 0.90 | AKT1 (0.70) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL31455900 | 0.90 | AKT1 (0.81) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL27260783 | 0.88 | AKT1 (0.66) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL30826714 | 0.88 | AKT1 (0.73) | AKT1AKT2AKT3CYP2C9CYP2C8 | |
| SCHEMBL30826583 | 0.88 | AKT1 (0.73) | AKT1AKT2AKT3CYP2C9CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064026-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-28 | — | — | WO | disclosed |