Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23202829 | 1.00 | PDE5A (0.46) | PDE5AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL23202898 | 0.88 | KMT2A (0.47) | PDE5AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL30827818 | 0.88 | KMT2A (0.47) | PDE5AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL30827828 | 0.86 | PDE5A (0.56) | PDE5AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL23202919 | 0.86 | PDE5A (0.56) | PDE5AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL23202880 | 0.86 | CCNC (0.44) | PDE5AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL30827806 | 0.86 | CCNC (0.44) | PDE5AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL29199911 | 0.84 | KMT2A (0.52) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL23202846 | 0.82 | CCNC (0.55) | PDE5AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL30827823 | 0.82 | CCNC (0.55) | PDE5AMAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802495-B1 | 4-(2-((2-CHLOROQUINOLIN-4-YL)AMINO)ETHYL)BENZENESULFONAMIDE DERIVATIVES AS STAT3 INHIBITORS FOR THE TREATMENT OF CANCER | C&C RES LAB (KR) | 2025-07-02 | — | — | EP | claimed |
| CN-112204010-B | Heterocyclic derivatives and uses thereof | C&C新药研究所 | 2024-03-19 | — | — | CN | claimed |
| CN-112204010-B | Heterocyclic derivatives and uses thereof | C&C新药研究所 | 2024-03-19 | — | — | CN | disclosed |