Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27175834 | 1.00 | BTK (0.33) | BTKJAK3 | |
| SCHEMBL30827939 | 0.91 | BTK (0.33) | BTKJAK3 | |
| SCHEMBL30828005 | 0.91 | BTK (0.33) | BTKJAK3 | |
| SCHEMBL24832847 | 0.91 | BTK (0.33) | BTKJAK3 | |
| SCHEMBL24834047 | 0.91 | BTK (0.33) | BTKJAK3 | |
| SCHEMBL24833017 | 0.91 | BTK (0.33) | BTKJAK3 | |
| SCHEMBL30827944 | 0.91 | BTK (0.33) | BTKJAK3 | |
| SCHEMBL27175859 | 0.91 | BTK (0.34) | BTKJAK3 | |
| SCHEMBL30827916 | 0.90 | HRH3 (0.33) | BTKJAK3 | |
| SCHEMBL27175832 | 0.90 | HRH3 (0.33) | BTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4342892-A1 | BRUTON'S TYROSINE KINASE AND MUTANT DEGRADER, COMPOSITION AND APPLICATION THEREOF | Hangzhou Healzen Therapeutics Co., Ltd. (CN) | 2024-03-27 | — | — | EP | disclosed |