Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 10/20 | 0.70 |
| ▸ | INSR | P06213 | 8/20 | 0.70 |
| ▸ | IGF1R | P08069 | 5/20 | 0.67 |
| ▸ | MAP4K1 | Q92918 | 10/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23116181 | 1.00 | ALK (0.70) | ALKINSRIGF1RMAP4K1 | |
| SCHEMBL22462158 | 0.91 | ALK (0.71) | ALKINSRIGF1RMAP4K1 | |
| SCHEMBL22462144 | 0.90 | ALK (0.71) | ALKINSRIGF1RMAP4K1 | |
| SCHEMBL25566394 | 0.89 | ALK (0.63) | ALKINSRIGF1RMAP4K1 | |
| SCHEMBL25565571 | 0.89 | ALK (0.65) | ALKINSRIGF1RMAP4K1 | |
| SCHEMBL25575516 | 0.89 | MAP4K1 (0.64) | ALKINSRIGF1RMAP4K1 | |
| SCHEMBL25566246 | 0.88 | ALK (0.67) | ALKINSRIGF1RMAP4K1 | |
| SCHEMBL13832407 | 0.88 | ALK (0.62) | ALKINSRIGF1RMAP4K1 | |
| SCHEMBL25566395 | 0.88 | ALK (0.64) | ALKINSRIGF1RMAP4K1 | |
| SCHEMBL25565573 | 0.87 | ALK (0.68) | ALKINSRIGF1RMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3715343-B1 | DIPHENYLAMINOPYRIMIDINE COMPOUND FOR INHIBITING KINASE ACTIVITY | SHENZHEN TARGETRX INC (CN) | 2024-02-14 | — | — | EP | disclosed |