SCHEMBL30829207

SCHEMBL30829207

CC(C)(C)[Si](C)(C)Oc1ccc2c(c1)-c1cc(O[Si](C)(C)C(C)(C)C)ccc1C21c2ccccc2-c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 11/20 0.44
CA12 O43570 4/20 0.41
CA1 P00915 4/20 0.41
CA9 Q16790 4/20 0.41
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
OPRK1 P41145 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PREP P48147 2/20 0.34
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27392258 0.89 CYP3A4 (0.41) PDK2CA12CA1CA9MEN1
SCHEMBL30829199 0.89 CYP3A4 (0.41) PDK2CA12CA1CA9MEN1
SCHEMBL30829198 0.83 CA12 (0.46) PDK2CA12CA1CA9KDM4E
SCHEMBL27393057 0.82 CA12 (0.43) PDK2CA12CA1CA9HSP90AA1
SCHEMBL27392579 0.75 PDK2 (0.66) PDK2CA1CA9KDM4EMEN1
SCHEMBL30829197 0.75 PDK2 (0.66) PDK2CA1CA9KDM4EMEN1
SCHEMBL8675809 0.74 CA12 (0.49) CA12CA1CA9LMNAMAPT
SCHEMBL19849703 0.72 CYP3A4 (0.47) CA12CA1CA9MEN1LMNA
SCHEMBL27392150 0.72 CYP3A4 (0.65) CA12CA1CA9MEN1LMNA
SCHEMBL12017833 0.72 CA1 (0.59) CA12CA1CA9KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608895-A1 HIGH TEMPERATURE DIELECTRIC POLYMERS AND FILMS The Scripps Research Institute (US) 2025-09-03 EP disclosed
WO-2024091684-A1 POLYSULFATE AND POLYSULFONATE POLYMERS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-05-02 WO disclosed