SCHEMBL30829753

SCHEMBL30829753

Fc1cc(Cl)c2scnc2c1Br

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.34
CSNK2A1 P68400 1/20 0.32
EPHB4 P54760 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28892143 1.00 GRM4 (0.34) GRM4CSNK2A1EPHB4
SCHEMBL28892209 0.78 GRM4 (0.32) GRM4CSNK2A1
SCHEMBL30002455 0.78 GRM4 (0.32) GRM4CSNK2A1
SCHEMBL28892462 0.75 GRM4 (0.35) GRM4CSNK2A1
SCHEMBL30829743 0.75 GRM4 (0.35) GRM4CSNK2A1
SCHEMBL25293669 0.73
SCHEMBL20176214 0.71 PI4KA (0.33)
SCHEMBL15968204 0.71
SCHEMBL25287962 0.69
SCHEMBL30311877 0.69 SMN1; SMN2 (0.51)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232144-B Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof 长春金赛药业有限责任公司 2024-04-02 CN disclosed