Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.53 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984563 | 1.00 | CSNK1D (0.53) | CSNK1DFOSJUNNFKB1NFKB2 | |
| SCHEMBL28059191 | 0.84 | CSNK1D (0.58) | CSNK1DFOSJUNNFKB1NFKB2 | |
| SCHEMBL22835196 | 0.83 | HSP90AA1 (0.54) | CSNK1DNFKB1NFKB2RELAMAOA | |
| SCHEMBL29652040 | 0.83 | HSP90AA1 (0.54) | CSNK1DNFKB1NFKB2RELAMAOA | |
| SCHEMBL26984530 | 0.83 | CSNK1D (0.57) | CSNK1DFOSJUNNFKB1NFKB2 | |
| SCHEMBL1015157 | 0.83 | CSNK1D (0.43) | CSNK1DFOSJUNNFKB1NFKB2 | |
| SCHEMBL30830217 | 0.83 | CSNK1D (0.57) | CSNK1DFOSJUNNFKB1NFKB2 | |
| SCHEMBL26984291 | 0.81 | CSNK1D (0.58) | CSNK1DFOSJUNNFKB1NFKB2 | |
| SCHEMBL31466879 | 0.81 | CYP1A2 (0.64) | CSNK1DFOSJUNNFKB1NFKB2 | |
| SCHEMBL26984728 | 0.81 | CYP1A2 (0.64) | CSNK1DFOSJUNNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551555-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | Vividion Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010782-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |