Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 2/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26961878 | 0.93 | POLB (0.35) | SRCPOLBMAPTP2RX3NPY1R | |
| SCHEMBL29796826 | 0.93 | POLB (0.35) | SRCPOLBMAPTP2RX3NPY1R | |
| SCHEMBL29796865 | 0.91 | POLB (0.36) | SRCPOLBMAPTP2RX3NPY1R | |
| SCHEMBL26962240 | 0.91 | POLB (0.36) | SRCPOLBMAPTP2RX3NPY1R | |
| SCHEMBL26961742 | 0.89 | SRC (0.33) | SRCPOLBMAPTP2RX3NPY1R | |
| SCHEMBL29796949 | 0.88 | POLB (0.35) | SRCPOLBMAPTP2RX3NPY1R | |
| SCHEMBL26962041 | 0.88 | POLB (0.35) | SRCPOLBMAPTP2RX3NPY1R | |
| SCHEMBL26961647 | 0.88 | POLB (0.35) | SRCPOLBMAPTP2RX3NPY1R | |
| SCHEMBL29796952 | 0.88 | SRC (0.34) | SRCPOLBMAPTP2RX3NPY1R | |
| SCHEMBL26962058 | 0.88 | SRC (0.34) | SRCPOLBMAPTP2RX3NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568958-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033388-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |