Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20812035 | 0.92 | CRBN (0.54) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| Hydrochloric Acid SCHEMBL19585786 | 0.90 | CRBN (0.53) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| Water SCHEMBL28335951 | 0.90 | CRBN (0.53) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| Trifluoroacetic Acid SCHEMBL31630885 | 0.80 | CRBN (0.46) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| SCHEMBL20463179 | 0.79 | CRBN (0.43) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| SCHEMBL20812349 | 0.78 | CRBN (0.57) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| SCHEMBL20812624 | 0.78 | CRBN (0.57) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| SCHEMBL19359470 | 0.76 | CRBN (0.56) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| SCHEMBL30817357 | 0.76 | CRBN (0.49) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| Trifluoroacetic Acid SCHEMBL31630914 | 0.76 | CRBN (0.42) | CRBNDDB1ALDH1A1TDP1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |