Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.64 |
| ▸ | IKZF2 | Q9UKS7 | 14/20 | 0.60 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22511594 | 1.00 | CRBN (0.64) | CRBNIKZF2IKZF1 | |
| SCHEMBL31736941 | 1.00 | CRBN (0.64) | CRBNIKZF2IKZF1 | |
| SCHEMBL31736853 | 1.00 | CRBN (0.64) | CRBNIKZF2IKZF1 | |
| Hydrochloric Acid SCHEMBL31025933 | 0.99 | CRBN (0.62) | CRBNIKZF2IKZF1 | |
| SCHEMBL31021072 | 0.95 | CRBN (0.62) | CRBNIKZF2IKZF1 | |
| SCHEMBL21340288 | 0.95 | CRBN (0.62) | CRBNIKZF2IKZF1 | |
| SCHEMBL20936153 | 0.95 | CRBN (0.62) | CRBNIKZF2IKZF1 | |
| SCHEMBL20935999 | 0.95 | CRBN (0.62) | CRBNIKZF2IKZF1 | |
| SCHEMBL31021086 | 0.95 | CRBN (0.62) | CRBNIKZF2IKZF1 | |
| SCHEMBL24319424 | 0.93 | CRBN (0.66) | CRBNIKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |