Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 6/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.33 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 7/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.32 |
| ▸ | BRD1 | O95696 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30830557 | 0.92 | KAT2B (0.38) | DDB1CRBNSETDB1KAT2BBRD9 | |
| SCHEMBL30831022 | 0.92 | KAT2B (0.38) | DDB1CRBNSETDB1KAT2BBRD9 | |
| SCHEMBL30831103 | 0.89 | KAT2B (0.42) | DDB1CRBNKAT2BBRD9BRD1 | |
| SCHEMBL30830850 | 0.84 | KAT2B (0.53) | DDB1CRBNKAT2BBRD9BRD1 | |
| SCHEMBL30830914 | 0.84 | KAT2B (0.53) | KAT2BBRD9BRD1ACHEBRPF1 | |
| SCHEMBL30830799 | 0.83 | KAT2B (0.41) | DDB1CRBNKAT2BBRD9BRD1 | |
| SCHEMBL30830566 | 0.81 | KAT2B (0.38) | DDB1CRBNKAT2BBRD9BRD1 | |
| SCHEMBL30830510 | 0.81 | KAT2B (0.34) | DDB1CRBNKAT2BBRD9BRD1 | |
| SCHEMBL30830534 | 0.80 | KAT2B (0.37) | DDB1CRBNKAT2BBRD9BRD1 | |
| SCHEMBL30830890 | 0.80 | KAT2B (0.39) | DDB1CRBNKAT2BBRD9BRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |