SCHEMBL30830808

SCHEMBL30830808

CN1C[C@H](Nc2cnn(C)c(=O)c2Cl)C[C@H](c2ccc(CN3CCC4(CC3)CCN(c3ccc(C5CCC(=O)NC5=O)c(F)c3)CC4)cc2)C1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KAT2B Q92831 20/20 0.47
▸ BRD9 Q9H8M2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30830636 0.93 KAT2B (0.47) KAT2BBRD9
SCHEMBL30830704 0.93 KAT2B (0.48) KAT2BBRD9
SCHEMBL30830670 0.92 KAT2B (0.46) KAT2BBRD9
SCHEMBL30830512 0.91 KAT2B (0.52) KAT2BBRD9
SCHEMBL30830673 0.91 KAT2B (0.52) KAT2BBRD9
SCHEMBL30830912 0.90 KAT2B (0.49) KAT2BBRD9
SCHEMBL30830580 0.89 KAT2B (0.45) KAT2BBRD9
SCHEMBL30830697 0.89 KAT2B (0.46) KAT2BBRD9
SCHEMBL30830862 0.89 KAT2B (0.47) KAT2BBRD9
SCHEMBL30830831 0.88 KAT2B (0.40) KAT2BBRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581025-A1 PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS Auron Therapeutics, Inc. (US) 2025-07-09 — — EP disclosed
WO-2024050078-A1 PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS AURON THERAPEUTICS, INC. (US) 2024-03-07 — — WO disclosed
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