SCHEMBL30830903

SCHEMBL30830903

Cn1nc(C2CCC(=O)NC2=O)c2ccc(N3CCC4(CCN(C(=O)OC(C)(C)C)CC4)CC3)cc21

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 16/20 0.69
▸ CRBN Q96SW2 16/20 0.69
▸ GPR119 Q8TDV5 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30706226 0.93 DDB1 (0.75) DDB1CRBNGPR119
SCHEMBL30768785 0.93 DDB1 (0.75) DDB1CRBNGPR119
SCHEMBL30776681 0.93 DDB1 (0.75) DDB1CRBNGPR119
SCHEMBL25586739 0.93 DDB1 (0.75) DDB1CRBNGPR119
SCHEMBL30706095 0.92 CRBN (0.61) DDB1CRBNGPR119
SCHEMBL26927476 0.92 CRBN (0.61) DDB1CRBNGPR119
SCHEMBL31513034 0.91 DDB1 (0.60) DDB1CRBNGPR119
SCHEMBL31513004 0.91 DDB1 (0.60) DDB1CRBNGPR119
SCHEMBL30731868 0.91 DDB1 (0.60) DDB1CRBNGPR119
SCHEMBL26925754 0.91 DDB1 (0.60) DDB1CRBNGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581025-A1 PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS Auron Therapeutics, Inc. (US) 2025-07-09 — — EP disclosed
WO-2024220843-A1 TECHNOLOGIES TARGETING CELL STATES AURON THERAPEUTICS, INC. (US) 2024-10-24 — — WO disclosed
WO-2024050078-A1 PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS AURON THERAPEUTICS, INC. (US) 2024-03-07 — — WO disclosed
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