Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31091756 | 1.00 | KDM4D (0.45) | KDM4DTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL31091687 | 0.86 | KMT2A (0.42) | GAABTKKMT2AL3MBTL1F2R | |
| SCHEMBL17916741 | 0.86 | KDM1A (0.54) | BTKKMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL21232571 | 0.83 | KMT2A (0.49) | KDM4DTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL21221554 | 0.83 | KDM1A (0.48) | KDM4DTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL21232465 | 0.83 | KDM1A (0.48) | KDM4DTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL21232441 | 0.83 | KMT2A (0.49) | KDM4DTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL21232595 | 0.81 | BTK (0.52) | KDM4DTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL22382254 | 0.81 | BTK (0.52) | KDM4DTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL21221573 | 0.81 | BTK (0.52) | KDM4DTSHRHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024220843-A1 | TECHNOLOGIES TARGETING CELL STATES | AURON THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |