Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 19/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30830502 | 0.91 | KAT2B (0.67) | KAT2B | |
| SCHEMBL30830660 | 0.82 | KAT2B (0.46) | KAT2B | |
| SCHEMBL17571681 | 0.80 | KAT2B (1.00) | KAT2B | |
| SCHEMBL30830988 | 0.72 | GRM5 (0.47) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30830560 | 0.72 | KAT2B (0.73) | KAT2B | |
| SCHEMBL30830795 | 0.72 | KAT2B (0.73) | KAT2B | |
| SCHEMBL30830923 | 0.72 | KAT2B (0.56) | KAT2B | |
| SCHEMBL19377001 | 0.71 | KAT2B (0.67) | KAT2BSMN1; SMN2 | |
| SCHEMBL17571551 | 0.71 | KAT2B (1.00) | KAT2B | |
| SCHEMBL30830993 | 0.70 | KAT2B (0.51) | KAT2BALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581025-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | Auron Therapeutics, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050078-A1 | PYRIDAZINON DERIVATIVES AS KAT2 DEGRADERS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | AURON THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |