Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.41 |
| ▸ | CACNG8 | Q8WXS5 | 4/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22160850 | 1.00 | MAPK13 (0.44) | MAPK13MAPK12MAPK11MAPK14GRIA1 | |
| SCHEMBL17653262 | 0.74 | KMT2A (0.49) | MAPTALPLALPIALPGGAA | |
| SCHEMBL12138257 | 0.73 | AR (0.46) | GRIA1CACNG8PDE3BPDE3AMAPT | |
| SCHEMBL17653277 | 0.72 | KMT2A (0.51) | MAPTGAAKMT2APOLBSMN1; SMN2 | |
| SCHEMBL17653363 | 0.71 | GAA (0.56) | MAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL17653325 | 0.71 | GAA (0.58) | GRIA1CACNG8MAPTGAAKMT2A | |
| SCHEMBL7009591 | 0.70 | CYP3A4 (0.48) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL30936642 | 0.69 | MAPK13 (0.43) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL5741661 | 0.69 | MAPK13 (0.43) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL15268120 | 0.69 | CHEK1 (0.48) | MAPK13MAPK12MAPK11MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315735-B | Dihydrobenzimidazolone | C4医药公司 | 2024-03-08 | — | — | CN | disclosed |