Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | AOC2 | O75106 | 1/20 | 0.38 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832844 | 0.81 | CRBN (0.47) | CRBNACVR1RAB9ANPC1KDM4E | |
| SCHEMBL20777386 | 0.81 | CRBN (0.47) | CRBNACVR1RAB9ANPC1KDM4E | |
| SCHEMBL30832868 | 0.74 | CRBN (0.55) | CRBNKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23874010 | 0.73 | ESR1 (0.46) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL20772661 | 0.72 | CRBN (0.55) | CRBNACVR1KDM4EALDH1A1HPGD | |
| SCHEMBL24961922 | 0.68 | KDM4E (0.45) | ACVR1KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL13965104 | 0.67 | RECQL (0.52) | RAB9AKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL21081279 | 0.67 | MAPK10 (0.46) | RAB9AKDM4EALDH1A1HPGDESR1 | |
| SCHEMBL8671615 | 0.67 | HTT (0.54) | — | |
| SCHEMBL18999449 | 0.66 | RECQL (0.61) | RAB9AKDM4EALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111315735-B | Dihydrobenzimidazolone | C4医药公司 | 2024-03-08 | — | — | CN | disclosed |