Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21856128 | 1.00 | PPM1D (0.32) | PPM1D | |
| SCHEMBL21952182 | 1.00 | PPM1D (0.32) | PPM1D | |
| SCHEMBL22799205 | 1.00 | PPM1D (0.32) | PPM1D | |
| SCHEMBL21631570 | 1.00 | PPM1D (0.32) | PPM1D | |
| SCHEMBL19641298 | 0.89 | NAMPT (0.37) | — | |
| SCHEMBL18392338 | 0.89 | NAMPT (0.37) | — | |
| SCHEMBL16925331 | 0.89 | NAMPT (0.37) | — | |
| SCHEMBL22084447 | 0.89 | NAMPT (0.37) | — | |
| SCHEMBL21918484 | 0.89 | NAMPT (0.37) | — | |
| SCHEMBL29467488 | 0.89 | NAMPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448923-B | Pyrimidine-fused ring compound, preparation method and application thereof | 上海青煜医药科技有限公司 | 2024-03-22 | — | — | CN | disclosed |