Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.50 |
| ▸ | STS | P08842 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17948873 | 1.00 | POLB (0.56) | POLBGPR119STSKDM4EPKM | |
| SCHEMBL17942534 | 0.84 | CHRM1 (0.43) | FAAH | |
| SCHEMBL1475228 | 0.80 | KDM4E (0.53) | GPR119STSKDM4EPKM | |
| SCHEMBL17942518 | 0.80 | POLB (0.55) | POLBGPR119STSFNTAFNTB | |
| SCHEMBL29529692 | 0.80 | POLB (0.55) | POLBGPR119STSFNTAFNTB | |
| SCHEMBL17948871 | 0.79 | POLB (0.56) | POLBGPR119KDM4EPKMFNTA | |
| SCHEMBL15940947 | 0.78 | POLB (0.63) | POLBGPR119STSKDM4EFNTA | |
| SCHEMBL29529409 | 0.77 | KDM4E (0.50) | GPR119STSKDM4EPKM | |
| SCHEMBL17948970 | 0.77 | KDM4E (0.50) | GPR119STSKDM4EPKM | |
| SCHEMBL23330142 | 0.77 | STS (0.47) | GPR119STSKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164961-A | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111393414-B | 4-Methylsulfonyl substituted piperidine urea compounds for the treatment of Dilated Cardiomyopathy (DCM) | 迈奥卡迪亚公司 | 2024-05-07 | — | — | CN | disclosed |