Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 3/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190706 | 1.00 | AXL (0.41) | AXLPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL6745979 | 0.78 | KDM4E (0.43) | PDPK1FGFR1GSK3BGSK3AKDM4E | |
| SCHEMBL30619334 | 0.78 | KDM4E (0.43) | PDPK1FGFR1GSK3BGSK3AKDM4E | |
| SCHEMBL22890269 | 0.76 | GSK3B (0.46) | AXLPDPK1AAK1JAK2FGFR1 | |
| SCHEMBL31422750 | 0.76 | GSK3B (0.46) | AXLPDPK1AAK1JAK2FGFR1 | |
| SCHEMBL2463747 | 0.75 | GSK3B (0.37) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL3524623 | 0.74 | PDPK1 (0.46) | AXLPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28400373 | 0.73 | PDPK1 (0.49) | AXLPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL25274990 | 0.73 | GSK3B (0.43) | AXLPDPK1AAK1JAK2FGFR1 | |
| SCHEMBL2471366 | 0.73 | GSK3B (0.47) | AXLPRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |