Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374982 | 0.82 | MAPT (0.57) | MAPTHPGDCNR2POLBCDK2 | |
| SCHEMBL30833717 | 0.80 | GSK3B (0.48) | MAPTHPGDCDK2MEN1KMT2A | |
| SCHEMBL27771844 | 0.79 | MAPT (0.55) | MAPTHPGDCNR2POLBCDK2 | |
| SCHEMBL8671558 | 0.78 | KCNH2 (0.53) | MAPTHPGDCNR2KCNH2POLB | |
| SCHEMBL18113557 | 0.76 | MAPT (0.57) | MAPTHPGDCNR2POLBCDK2 | |
| SCHEMBL31423204 | 0.76 | MAPT (0.57) | MAPTHPGDCNR2POLBCDK2 | |
| SCHEMBL9229130 | 0.75 | KDM4E (0.39) | HPGDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3343737 | 0.74 | MAPT (0.55) | MAPTHPGDCNR2KCNH2POLB | |
| SCHEMBL3346790 | 0.73 | MAPT (0.57) | MAPTHPGDCNR2POLBCDK2 | |
| SCHEMBL6683966 | 0.71 | MAPT (0.47) | MAPTKCNH2ACHEALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |