Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 6/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | ULK1 | O75385 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | AQP1 | P29972 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375399 | 0.83 | ZAP70 (0.46) | ZAP70CDK7CDK9ALKULK1 | |
| SCHEMBL31251230 | 0.81 | CDK7 (0.53) | ZAP70CDK7CDK9ALKULK1 | |
| SCHEMBL375360 | 0.81 | ZAP70 (0.61) | ZAP70CDK7CDK9ALKULK1 | |
| SCHEMBL4095652 | 0.79 | IGF1R (0.50) | ZAP70CDK7CDK9ALKULK1 | |
| SCHEMBL375527 | 0.79 | IGF1R (0.50) | ZAP70CDK7CDK9ALKULK1 | |
| SCHEMBL4103133 | 0.78 | IGF1R (0.49) | ZAP70CDK7CDK9ALKULK1 | |
| SCHEMBL29190691 | 0.78 | ALK (0.59) | ZAP70CDK7CDK9ALKULK1 | |
| SCHEMBL4094489 | 0.78 | ZAP70 (0.48) | ZAP70CDK7CDK9ALKULK1 | |
| SCHEMBL25056256 | 0.75 | ZAP70 (0.48) | ZAP70CDK7CDK9ALKULK1 | |
| SCHEMBL31251181 | 0.75 | IGF1R (0.46) | ZAP70CDK7CDK9ALKULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |