SCHEMBL30834282

SCHEMBL30834282

O=C(O)c1ccc(-c2cc(CN3CCOCC3)c3ccc(Cl)cc3n2)cc1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MOK Q9UQ07 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30834293 0.92 MOK (0.72) MOK
SCHEMBL31590551 0.88 MOK (0.68) MOK
SCHEMBL31590890 0.87 MOK (0.66) MOK
SCHEMBL30834335 0.86 MOK (0.65) MOK
SCHEMBL31590313 0.85 MOK (0.69) MOK
SCHEMBL31590596 0.85 MOK (0.69) MOK
SCHEMBL31590462 0.85 MOK (0.74) MOK
SCHEMBL19475281 0.85 MOK (0.68) MOK
SCHEMBL31590498 0.85 MOK (0.68) MOK
SCHEMBL31590624 0.85 MOK (0.68) MOK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594303-A1 QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF New York University (US) 2025-08-06 EP disclosed
CN-120051459-A Quinoline compounds as modulators of RAGE activity and uses thereof 纽约大学 2025-05-27 CN disclosed
WO-2024072870-A1 QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF NEW YORK UNIVERSITY (US) 2024-04-04 WO disclosed