SCHEMBL30834286

SCHEMBL30834286

CNC(C)c1ccc(-c2cc(CN3CCOCC3)c3ccc(C#N)cc3n2)cc1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MOK Q9UQ07 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30834283 0.86 MOK (0.60) MOK
SCHEMBL31590607 0.85 MOK (0.71) MOK
SCHEMBL30834307 0.85 MOK (0.70) MOK
SCHEMBL31590940 0.84 MOK (0.68) MOK
SCHEMBL19475414 0.83 MOK (0.70) MOK
SCHEMBL30834310 0.82 MOK (0.68) MOK
SCHEMBL30834321 0.81 MOK (0.69) MOK
SCHEMBL19475499 0.81 MOK (1.00) MOK
SCHEMBL31590319 0.81 MOK (0.57) MOK
SCHEMBL31590462 0.80 MOK (0.74) MOK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594303-A1 QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF New York University (US) 2025-08-06 EP disclosed
CN-120051459-A Quinoline compounds as modulators of RAGE activity and uses thereof 纽约大学 2025-05-27 CN disclosed
WO-2024072870-A1 QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF NEW YORK UNIVERSITY (US) 2024-04-04 WO disclosed