SCHEMBL30834754

CC(C)C[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	15/20	0.60

▸	NPY1R	P25929	9/20	0.60

▸	NPY5R	Q15761	8/20	0.60

▸	NPY2R	P49146	5/20	0.60

▸	TFPI	P10646	1/20	0.59

▸	BACE1	P56817	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30512654	0.92	NPY4R (0.62)	NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL29548324	0.90	TFPI (0.63)	NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30844091	0.89	NPY4R (0.63)	NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30904845	0.87	NPY4R (0.58)	NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL31419699	0.87	TFPI (0.71)	TFPIBACE1
SCHEMBL31141451	0.87	TFPI (0.65)	NPY4RNPY1RNPY5RTFPI
SCHEMBL29960067	0.87	NPY4R (0.62)	NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL31269521	0.87	NPY4R (0.64)	NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL30015428	0.86	NPY4R (0.63)	NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL22413050	0.86	NPY4R (0.65)	NPY4RNPY1RNPY5RNPY2RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240310391-A1	HDL-ASSOCIATED PROTEIN EXTRACTION AND DETECTION	CLEVELAND HEARTLAB, INC. (US)	2024-09-19	—	—	US	disclosed
US-11940452-B2	HDL-associated protein extraction and detection	CLEVELAND HEARTLAB, INC. (US)	2024-03-26	—	—	US	disclosed