Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.51 |
| ▸ | BACE1 | P56817 | 12/20 | 0.48 |
| ▸ | CTSD | P07339 | 3/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31097668 | 0.96 | FOLH1 (0.55) | FOLH1BACE1CTSDPTPN1BACE2 | |
| SCHEMBL30528151 | 0.96 | FOLH1 (0.55) | FOLH1BACE1CTSDPTPN1BACE2 | |
| SCHEMBL31097674 | 0.96 | FOLH1 (0.55) | FOLH1BACE1CTSDPTPN1BACE2 | |
| SCHEMBL31097736 | 0.96 | FOLH1 (0.55) | FOLH1BACE1CTSDPTPN1BACE2 | |
| SCHEMBL31484252 | 0.95 | BACE1 (0.53) | FOLH1BACE1CTSDGRIN2DGRIN3B | |
| SCHEMBL29616369 | 0.93 | BACE1 (0.50) | FOLH1BACE1CTSDGRIN2DGRIN3B | |
| SCHEMBL29679880 | 0.92 | FOLH1 (0.53) | FOLH1BACE1CTSDGRIN2DGRIN3B | |
| SCHEMBL29695600 | 0.92 | BACE1 (0.51) | BACE1CTSDGRIN2DGRIN3BGRIN1 | |
| SCHEMBL31484226 | 0.91 | FOLH1 (0.58) | FOLH1BACE1CTSDBACE2ERAP2 | |
| SCHEMBL30662327 | 0.91 | FOLH1 (0.58) | FOLH1BACE1CTSDBACE2ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240310391-A1 | HDL-ASSOCIATED PROTEIN EXTRACTION AND DETECTION | CLEVELAND HEARTLAB, INC. (US) | 2024-09-19 | — | — | US | disclosed |
| US-11940452-B2 | HDL-associated protein extraction and detection | CLEVELAND HEARTLAB, INC. (US) | 2024-03-26 | — | — | US | disclosed |