Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.43 |
| ▸ | PDCD1LG2 | Q9BQ51 | 14/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30836678 | 0.97 | CD274 (0.42) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30836746 | 0.96 | CD274 (0.43) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30836608 | 0.95 | CD274 (0.44) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30836681 | 0.94 | CD274 (0.43) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30836711 | 0.93 | CD274 (0.44) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30836597 | 0.93 | CD274 (0.44) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30836755 | 0.92 | CD274 (0.43) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30836747 | 0.91 | CD274 (0.45) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL29143954 | 0.91 | CD274 (0.43) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL30836600 | 0.90 | CD274 (0.44) | CD274PDCD1LG2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024069448-A1 | SUBSTITUTED 1-ARYLAMINOCARBONYL-1'-HETEROARYL COMPOUNDS, SUBSTITUTED 1-HETEROARYLAMINOCARBONYL-1'-HETEROARYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-04-04 | — | — | WO | disclosed |