⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL28839569 | 0.91 | — | — | |
| Propane SCHEMBL10956924 | 0.89 | TSHR (0.43) | — | |
| Propane SCHEMBL9246294 | 0.89 | — | — | |
| Propane SCHEMBL9248656 | 0.89 | TSHR (0.43) | — | |
| Propane SCHEMBL286506 | 0.89 | — | — | |
| Propane SCHEMBL1021 | 0.89 | — | — | |
| Propane SCHEMBL7711629 | 0.80 | — | — | |
| Propane SCHEMBL11076973 | 0.80 | — | — | |
| Propane SCHEMBL2245238 | 0.80 | — | — | |
| Propane SCHEMBL11463258 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042911-A1 | NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF | SPARK BIOPHARMA, INC. (KR) | 2025-02-06 | — | — | US | disclosed |
| EP-4365175-A1 | NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF | Spark Biopharma, Inc. (KR) | 2024-05-08 | — | — | EP | disclosed |
| CN-117897386-A | Benzopyran derivatives and uses thereof | 斯帕克生物制药有限公司 | 2024-04-16 | — | — | CN | disclosed |