Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30837107 | 0.90 | EGFR (0.49) | EGFRFGFR1RIPK2NOD2 | |
| SCHEMBL30837125 | 0.89 | EGFR (0.48) | EGFRFGFR1RIPK2NOD2 | |
| SCHEMBL30836982 | 0.89 | RIPK2 (0.52) | EGFRFGFR1RIPK2NOD2 | |
| SCHEMBL30837087 | 0.88 | EGFR (0.48) | EGFRFGFR1RIPK2NOD2 | |
| SCHEMBL30837015 | 0.88 | EGFR (0.51) | EGFRFGFR1TTK | |
| SCHEMBL30837070 | 0.88 | EGFR (0.49) | EGFRFGFR1 | |
| SCHEMBL30837022 | 0.87 | EGFR (0.47) | EGFRFGFR1RIPK2NOD2 | |
| SCHEMBL30837117 | 0.87 | EGFR (0.47) | EGFRFGFR1RIPK2NOD2 | |
| SCHEMBL30837126 | 0.87 | EGFR (0.50) | EGFRFGFR1RIPK2NOD2 | |
| SCHEMBL30837023 | 0.86 | EGFR (0.55) | EGFRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073745-A1 | INHIBITORS OF EGFR OR HER2 AND METHODS OF USE | ARBELLA THERAPEUTICS, LLC (US) | 2024-04-04 | — | — | WO | disclosed |