Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 0.70 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 0.70 |
| ▸ | PDE8A | O60658 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101006 | 1.00 | PDE7A (0.70) | PDE7APDE7BPDE8ASMN1; SMN2TSHR | |
| SCHEMBL100388 | 0.94 | PDE7A (0.72) | PDE7APDE7BPDE8ATSHRHTT | |
| SCHEMBL30837877 | 0.93 | PDE7A (0.80) | PDE7APDE7BPDE8ASMN1; SMN2TSHR | |
| SCHEMBL101100 | 0.93 | PDE7A (0.80) | PDE7APDE7BPDE8ASMN1; SMN2TSHR | |
| SCHEMBL100920 | 0.92 | PDE7A (0.71) | PDE7APDE7BPDE8ASMN1; SMN2TP53 | |
| SCHEMBL101155 | 0.91 | PDE7A (0.70) | PDE7APDE7BPDE8ASMN1; SMN2KDM4E | |
| SCHEMBL101156 | 0.91 | PDE7A (0.74) | PDE7APDE7BPDE8ASMN1; SMN2TSHR | |
| SCHEMBL101150 | 0.91 | PDE7A (0.70) | PDE7APDE7BPDE8A | |
| SCHEMBL101023 | 0.91 | PDE7A (0.70) | PDE7APDE7BPDE8ASMN1; SMN2TSHR | |
| SCHEMBL100429 | 0.90 | PDE7A (0.66) | PDE7APDE7BPDE8ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |