Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 9/20 | 0.73 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.54 |
| ▸ | PDE8A | O60658 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2683480 | 1.00 | PDE7A (0.73) | PDE7APDE7BPDE8AALDH1A1KDM4E | |
| SCHEMBL2682202 | 0.93 | PDE7A (0.64) | PDE7APDE7BPDE8AALDH1A1KDM4E | |
| SCHEMBL30837794 | 0.93 | PDE7A (0.64) | PDE7APDE7BPDE8AALDH1A1KDM4E | |
| SCHEMBL134836 | 0.90 | PDE7A (0.73) | PDE7APDE7BPDE8AALDH1A1KDM4E | |
| SCHEMBL100671 | 0.89 | PDE7A (0.77) | PDE7APDE7BPDE8AALDH1A1TP53 | |
| SCHEMBL585427 | 0.88 | PDE7A (0.76) | PDE7APDE7BPDE8AALDH1A1KDM4E | |
| SCHEMBL30837805 | 0.88 | PDE7A (0.91) | PDE7APDE7BPDE8ATP53RXFP1 | |
| SCHEMBL99906 | 0.88 | PDE7A (0.91) | PDE7APDE7BPDE8ATP53RXFP1 | |
| SCHEMBL581703 | 0.88 | PDE7A (0.60) | PDE7APDE7BPDE8AALDH1A1KDM4E | |
| SCHEMBL30837940 | 0.88 | PDE7A (0.60) | PDE7APDE7BPDE8AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |