Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 0.68 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 0.63 |
| ▸ | PDE8A | O60658 | 3/20 | 0.60 |
| ▸ | PDE1A | P54750 | 7/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 7/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL582915 | 1.00 | PDE7A (0.68) | PDE7APDE7BPDE8APDE1APDE1B | |
| SCHEMBL582470 | 0.93 | PDE7A (0.78) | PDE7APDE7BPDE8APDE1APDE1B | |
| SCHEMBL30837767 | 0.93 | PDE7A (0.78) | PDE7APDE7BPDE8APDE1APDE1B | |
| SCHEMBL582301 | 0.92 | PDE7A (0.67) | PDE7APDE7BPDE8APDE1APDE1B | |
| SCHEMBL7875095 | 0.91 | PDE7A (0.65) | PDE7APDE7BPDE8APDE1APDE1B | |
| SCHEMBL32681349 | 0.91 | PDE7A (0.67) | PDE7APDE7BPDE8APDE1APDE1B | |
| SCHEMBL583085 | 0.91 | PDE7A (0.67) | PDE7APDE7BPDE8APDE1APDE1B | |
| SCHEMBL583197 | 0.91 | PDE7A (0.63) | PDE7APDE7BPDE8APDE1APDE1B | |
| SCHEMBL32681331 | 0.91 | PDE7A (0.63) | PDE7APDE7BPDE8APDE1APDE1B | |
| SCHEMBL30837847 | 0.90 | PDE7A (0.68) | PDE7APDE7BPDE8AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |