Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 1.00 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 1.00 |
| ▸ | PDE8A | O60658 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL581641 | 1.00 | PDE7A (1.00) | PDE7APDE7BPDE8AKMT2AMEN1 | |
| SCHEMBL139609 | 0.90 | PDE7A (0.82) | PDE7APDE7BPDE8AKMT2AMEN1 | |
| SCHEMBL30837814 | 0.90 | PDE7A (0.82) | PDE7APDE7BPDE8AKMT2AMEN1 | |
| SCHEMBL2681821 | 0.90 | PDE7A (0.82) | PDE7APDE7BPDE8AKMT2AMEN1 | |
| SCHEMBL581680 | 0.89 | PDE7A (0.81) | PDE7APDE7BPDE8AKMT2AMEN1 | |
| SCHEMBL30837880 | 0.89 | PDE7A (0.81) | PDE7APDE7BPDE8AKMT2AMEN1 | |
| SCHEMBL7886324 | 0.89 | PDE7A (0.80) | PDE7APDE7BPDE8AKMT2AMEN1 | |
| SCHEMBL582248 | 0.89 | PDE7A (0.79) | PDE7APDE7BPDE8AKMT2AMEN1 | |
| SCHEMBL581681 | 0.89 | PDE7A (0.79) | PDE7APDE7BPDE8AKMT2AMEN1 | |
| SCHEMBL30837929 | 0.89 | PDE7A (0.79) | PDE7APDE7BPDE8AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |