Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 0.85 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 0.85 |
| ▸ | PDE8A | O60658 | 3/20 | 0.85 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101109 | 1.00 | PDE7A (0.85) | PDE7APDE7BPDE8ACSF1RMEN1 | |
| SCHEMBL100181 | 0.95 | PDE7A (0.86) | PDE7APDE7BPDE8ACSF1RMEN1 | |
| SCHEMBL100320 | 0.94 | PDE7A (0.84) | PDE7APDE7BPDE8ACSF1RMEN1 | |
| SCHEMBL30837773 | 0.94 | PDE7A (0.84) | PDE7APDE7BPDE8ACSF1RMEN1 | |
| SCHEMBL100704 | 0.92 | PDE7A (1.00) | PDE7APDE7BPDE8AMEN1MAPT | |
| SCHEMBL30837881 | 0.92 | PDE7A (1.00) | PDE7APDE7BPDE8AMEN1MAPT | |
| SCHEMBL100171 | 0.92 | PDE7A (0.90) | PDE7APDE7BPDE8AMEN1MAPT | |
| SCHEMBL101113 | 0.91 | PDE7A (0.82) | PDE7APDE7BPDE8ACSF1RMEN1 | |
| SCHEMBL101023 | 0.91 | PDE7A (0.70) | PDE7APDE7BPDE8ACSF1RNPC1 | |
| SCHEMBL100224 | 0.91 | PDE7A (0.89) | PDE7APDE7BPDE8AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |