Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 10/20 | 0.66 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 0.66 |
| ▸ | PDE8A | O60658 | 3/20 | 0.66 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL136165 | 1.00 | PDE7A (0.66) | PDE7APDE7BPDE8ACSF1RPOLB | |
| SCHEMBL100208 | 0.94 | PDE7A (0.66) | PDE7APDE7BPDE8ACSF1RPOLB | |
| SCHEMBL101150 | 0.94 | PDE7A (0.70) | PDE7APDE7BPDE8ACSF1RNPC1 | |
| SCHEMBL30837812 | 0.93 | PDE7A (0.65) | PDE7APDE7BPDE8ACSF1RPOLB | |
| SCHEMBL100296 | 0.93 | PDE7A (0.65) | PDE7APDE7BPDE8ACSF1RPOLB | |
| SCHEMBL100417 | 0.92 | PDE7A (0.69) | PDE7APDE7BPDE8ACSF1RNPC1 | |
| SCHEMBL101024 | 0.92 | PDE7A (0.63) | PDE7APDE7BPDE8ACSF1R | |
| SCHEMBL101023 | 0.91 | PDE7A (0.70) | PDE7APDE7BPDE8ACSF1RSMN1; SMN2 | |
| SCHEMBL100517 | 0.91 | PDE7A (0.62) | PDE7APDE7BPDE8ACSF1RPOLB | |
| SCHEMBL3756258 | 0.91 | PDE7A (0.64) | PDE7APDE7BPDE8ACSF1RPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572765-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | Mitodicure GmbH (DE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038089-A1 | USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE | MITODICURE GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |