SCHEMBL30838156

SCHEMBL30838156

CC1CC(c2cccc(NC(=O)c3cc(CNCC(C)(C)C)cn(CC4CC4)c3=O)c2)(c2nncn2C)C1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.51
▸ CBL P22681 14/20 0.49
▸ CBLC Q9ULV8 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30838252 0.93 CBLB (0.54) CBLBCBLCBLC
SCHEMBL30838208 0.91 CBLB (0.49) CBLBCBLCBLC
SCHEMBL30838272 0.91 CBLB (0.51) CBLBCBLCBLC
SCHEMBL30838160 0.86 CBLB (0.51) CBLBCBLCBLC
SCHEMBL30838331 0.86 CBLB (0.49) CBLBCBLCBLC
SCHEMBL30838288 0.86 CBLB (0.51) CBLBCBLCBLC
SCHEMBL31485875 0.85 CBLB (0.56) CBLBCBLCBLC
SCHEMBL30838229 0.82 CBLB (0.43) CBLBCBLCBLC
SCHEMBL30838216 0.82 CBLB (0.49) CBLBCBLCBLC
SCHEMBL30838318 0.82 CBLB (0.39) CBLBCBLCBLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573085-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS Glenmark Pharmaceuticals Limited (IN) 2025-06-25 — — EP claimed
CN-119546587-A Substituted pyridone compounds as CBL-B inhibitors 格兰玛克制药有限公司 2025-02-28 — — CN claimed
WO-2024038378-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS GLENMARK PHARMACEUTICALS LTD (IN) 2024-02-22 — — WO claimed
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