SCHEMBL30838182

SCHEMBL30838182

Cn1cnnc1C1(c2ccc(F)c(NC(=O)c3cc(CNCC4CC4)cn(CC(F)(F)F)c3=O)c2)CC2(CC2)C1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 11/20 0.33
▸ CBLC Q9ULV8 1/20 0.33
▸ CBL P22681 9/20 0.33
▸ KLKB1 P03952 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30838180 0.97 CBLB (0.33) CBLBCBLCCBLKLKB1
SCHEMBL30838309 0.95 CBLB (0.32) CBLBCBLCCBLKLKB1
SCHEMBL30838241 0.94 CBLB (0.37) CBLBCBLCCBL
SCHEMBL30838345 0.94 CBLB (0.33) CBLBCBLCCBLKLKB1
SCHEMBL30838341 0.93 CBLB (0.34) CBLBCBLCCBLKLKB1
SCHEMBL30838139 0.91 CBL (0.31) CBLBCBL
SCHEMBL30838334 0.91 CBLB (0.41) CBLBCBLCCBL
SCHEMBL30838221 0.91 CBLB (0.32) CBLBCBL
SCHEMBL30838185 0.88 CBLB (0.31) CBLBCBLCCBL
SCHEMBL30838193 0.88 CBLB (0.33) CBLBCBLCCBLKLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573085-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS Glenmark Pharmaceuticals Limited (IN) 2025-06-25 — — EP claimed
WO-2024038378-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS GLENMARK PHARMACEUTICALS LTD (IN) 2024-02-22 — — WO claimed
Send feedback