SCHEMBL30838196

SCHEMBL30838196

Cn1cnnc1C1(c2cccc(NC(=O)c3cc(C=O)cn(CC(F)(F)F)c3=O)c2)CC(C)(C)C1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 19/20 0.41
▸ CBL P22681 11/20 0.38
▸ CBLC Q9ULV8 1/20 0.38
▸ LMNA P02545 1/20 0.34
▸ GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30838372 0.93 CBLB (0.41) CBLBCBLCBLCLMNAGAA
SCHEMBL30838244 0.91 CBLB (0.52) CBLBCBLCBLC
SCHEMBL30838235 0.87 CBLB (0.39) CBLBCBLCBLC
SCHEMBL30838318 0.87 CBLB (0.39) CBLBCBLCBLC
SCHEMBL30838362 0.86 CBLB (0.39) CBLBCBLCBLC
SCHEMBL30838313 0.86 CBLB (0.43) CBLBCBLCBLC
SCHEMBL30838328 0.85 CBLB (0.40) CBLBCBLCBLC
SCHEMBL30838188 0.85 CBLB (0.43) CBLBCBLCBLC
SCHEMBL30838213 0.85 CBLB (0.39) CBLBCBLCBLC
SCHEMBL30838167 0.85 CBLB (0.45) CBLBCBLCBLC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573085-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS Glenmark Pharmaceuticals Limited (IN) 2025-06-25 — — EP disclosed
WO-2024038378-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS GLENMARK PHARMACEUTICALS LTD (IN) 2024-02-22 — — WO disclosed
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