SCHEMBL30838238

SCHEMBL30838238

C[C@H]1CCCN(Cc2cc(C(=O)Nc3cccc(C4(c5nncn5C)CC(F)(F)C4)c3)c(=O)n(CC(F)(F)F)c2)C1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.51
▸ CBLC Q9ULV8 3/20 0.51
▸ CBL P22681 10/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30838293 0.95 CBLB (0.51) CBLBCBLCCBL
SCHEMBL30838133 0.94 CBLB (0.51) CBLBCBLCCBL
SCHEMBL30838192 0.94 CBLB (0.50) CBLBCBLCCBL
SCHEMBL30838257 0.94 CBLB (0.56) CBLBCBLCCBL
SCHEMBL34468182 0.89 CBLB (0.52) CBLBCBLCCBL
SCHEMBL30838195 0.87 CBLB (0.51) CBLBCBLCCBL
SCHEMBL31485875 0.85 CBLB (0.56) CBLBCBLCCBL
SCHEMBL30838147 0.84 CBLB (0.44) CBLBCBLCCBL
SCHEMBL30838363 0.84 CBLB (0.50) CBLBCBLCCBL
SCHEMBL30838188 0.84 CBLB (0.43) CBLBCBLCCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573085-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS Glenmark Pharmaceuticals Limited (IN) 2025-06-25 — — EP claimed
WO-2024038378-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS GLENMARK PHARMACEUTICALS LTD (IN) 2024-02-22 — — WO claimed
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