SCHEMBL30838239

SCHEMBL30838239

Cn1cnnc1C1(c2ccc(F)c(NC(=O)c3cc(CNCC(C)(C)C)cn(CC(F)(F)F)c3=O)c2)CC(C)(C)C1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CBL P22681 4/20 0.31
▸ CBLB Q13191 4/20 0.31
▸ PDCD1 Q15116 1/20 0.30
▸ CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30838333 0.96 CBL (0.31) CBLCBLBPDCD1CD274
SCHEMBL30838379 0.94 CBL (0.31) CBLCBLB
SCHEMBL30838181 0.94 CBL (0.31) CBLCBLB
SCHEMBL30838139 0.94 CBL (0.31) CBLCBLB
SCHEMBL30838284 0.93 CBLB (0.31) CBLCBLB
SCHEMBL30838157 0.92 PDCD1 (0.33) CBLCBLBPDCD1CD274
SCHEMBL30838136 0.92 CBLB (0.31) CBLCBLBPDCD1CD274
SCHEMBL30838271 0.91 CBLB (0.40) CBLCBLB
SCHEMBL30838345 0.91 CBLB (0.33) CBLCBLB
SCHEMBL30838201 0.91 CBLB (0.32) CBLCBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573085-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS Glenmark Pharmaceuticals Limited (IN) 2025-06-25 — — EP claimed
WO-2024038378-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS GLENMARK PHARMACEUTICALS LTD (IN) 2024-02-22 — — WO claimed
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