SCHEMBL30838289

SCHEMBL30838289

CCC1(CC)CC(c2ccc(F)c(NC(=O)c3cc(CNCC4(CF)CC4)cn(CC(F)(F)F)c3=O)c2)(c2nncn2C)C1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBL P22681 1/20 0.30
▸ CBLB Q13191 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30838203 0.94 CBL (0.30) CBLCBLB
SCHEMBL30838378 0.93 CBLB (0.30) CBLCBLB
SCHEMBL30838205 0.93 — —
SCHEMBL30838184 0.92 CBLB (0.35) CBLCBLB
SCHEMBL30838351 0.91 CBLB (0.39) CBLCBLB
SCHEMBL30838341 0.90 CBLB (0.34) CBLCBLB
SCHEMBL30838360 0.90 CBLB (0.31) CBLCBLB
SCHEMBL30838215 0.89 PDCD1 (0.33) CBLCBLB
SCHEMBL30838253 0.86 CBLB (0.39) CBLCBLB
SCHEMBL30838132 0.85 CBLB (0.39) CBLCBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573085-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS Glenmark Pharmaceuticals Limited (IN) 2025-06-25 — — EP claimed
WO-2024038378-A1 SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS GLENMARK PHARMACEUTICALS LTD (IN) 2024-02-22 — — WO claimed
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