Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.77 |
| ▸ | MEN1 | O00255 | 8/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.60 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28967926 | 1.00 | KMT2A (0.77) | KMT2AMEN1GAAL3MBTL1POLB | |
| SCHEMBL28967922 | 1.00 | KMT2A (0.77) | KMT2AMEN1GAAL3MBTL1POLB | |
| SCHEMBL29045640 | 0.92 | KMT2A (0.69) | KMT2AMEN1GAAL3MBTL1POLB | |
| SCHEMBL29045637 | 0.92 | KMT2A (0.69) | KMT2AMEN1GAAL3MBTL1POLB | |
| SCHEMBL245319 | 0.87 | KMT2A (0.66) | KMT2AMEN1GAAL3MBTL1POLB | |
| SCHEMBL245318 | 0.87 | KMT2A (0.66) | KMT2AMEN1GAAL3MBTL1POLB | |
| SCHEMBL29045647 | 0.87 | KMT2A (1.00) | KMT2AMEN1GAAL3MBTL1POLB | |
| SCHEMBL29045646 | 0.87 | KMT2A (1.00) | KMT2AMEN1GAAL3MBTL1POLB | |
| SCHEMBL10035997 | 0.86 | KMT2A (0.81) | KMT2AMEN1GAAL3MBTL1POLB | |
| SCHEMBL28476008 | 0.86 | KMT2A (0.81) | KMT2AMEN1GAAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820323-A | Synthesis method of pyrazolone spiro-dihydropyrrole derivative | 安徽工程大学 | 2024-04-05 | — | — | CN | disclosed |