⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258122 | 0.66 | — | — | |
| SCHEMBL308904 | 0.64 | — | — | |
| SCHEMBL10368984 | 0.62 | — | — | |
| SCHEMBL50847 | 0.62 | — | — | |
| SCHEMBL64332 | 0.59 | — | — | |
| SCHEMBL6176989 | 0.59 | — | — | |
| SCHEMBL513580 | 0.59 | — | — | |
| SCHEMBL28661 | 0.59 | — | — | |
| SCHEMBL1451807 | 0.59 | — | — | |
| SCHEMBL562303 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819982-A1 | Radiation-sensitive composition | Olin Microelectronic Chemicals, Inc. (US) | 1998-01-21 | — | — | EP | claimed |
| US-4795755-A | ANTISECRETORY, ANTIULCER AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-03 | — | — | US | claimed |
| US-4748165-A | ANTISECRETORY AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-31 | — | — | US | claimed |
| US-4746672-A | HISTAMINE H-2 ANTAGONISTS WHICH INHIBIT GASTRIC ACID SECRETION | ICI AMERICAS INC. (US) | 1988-05-24 | — | — | US | claimed |
| US-4696933-A | INHIBIT GASTRIC ACID SECRETION | ICI AMERICAS INC. (GB) | 1987-09-29 | — | — | US | claimed |
| US-4665073-A | HISTAMINE H2-ANTAGONISTS | ICI AMERICAS INC. (GB) | 1987-05-12 | — | — | US | claimed |
| US-4657908-A | Carbonyl derivatives | ICI AMERICAS, INC. (US) | 1987-04-14 | — | — | US | claimed |
| EP-0060697-B1 | HETEROCYCLIC DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | claimed |
| EP-0060093-B1 | AMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-05-28 | — | — | EP | claimed |
| EP-0059597-B1 | GUANIDINO-SUBSTITUTED HETEROCYCLIC DERIVATIVES HAVING HISTAMINE H-2 ANTAGONIST ACTIVITY | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-04-23 | — | — | EP | claimed |
| EP-0065823-A1 | Heterocyclic guanidines as histamine H-2 antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | claimed |
| EP-0061318-A2 | Guanidinoheterocyclic derivatives as histamine H-2 antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-29 | — | — | EP | claimed |
| EP-0060697-A1 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060730-A2 | Bicyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060696-A1 | Nitrogen heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | claimed |
| EP-0060094-A2 | Guanidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | claimed |
| EP-0060093-A2 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | claimed |
| EP-0059597-A2 | Guanidino-substituted heterocyclic derivatives having histamine H-2 antagonist activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-08 | — | — | EP | claimed |
| EP-0053017-A1 | Amide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | claimed |
| EP-0045161-A1 | Amides of 4-oxo-5-amidohexanoic acid derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-03 | — | — | EP | claimed |