Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.64 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839313 | 1.00 | HTR2C (0.64) | HTR2CPRMT5MTNR1AMTNR1BHTR2A | |
| SCHEMBL29162339 | 1.00 | HTR2C (0.64) | HTR2CPRMT5MTNR1AMTNR1BHTR2A | |
| SCHEMBL29162343 | 1.00 | HTR2C (0.64) | HTR2CPRMT5MTNR1AMTNR1BHTR2A | |
| SCHEMBL29162369 | 0.99 | HTR2C (0.63) | HTR2CPRMT5MTNR1AMTNR1BHTR2A | |
| SCHEMBL25822826 | 0.99 | HTR2C (0.63) | HTR2CPRMT5MTNR1AMTNR1BHTR2A | |
| SCHEMBL30839316 | 0.99 | HTR2C (0.63) | HTR2CPRMT5MTNR1AMTNR1BHTR2A | |
| SCHEMBL30839296 | 0.99 | HTR2C (0.63) | HTR2CPRMT5MTNR1AMTNR1BHTR2A | |
| SCHEMBL25822817 | 0.97 | HTR2C (0.64) | HTR2CPRMT5MTNR1AMTNR1BHTR2A | |
| SCHEMBL30839305 | 0.90 | HTR2C (0.61) | HTR2CPRMT5MTNR1AMTNR1BHTR2A | |
| SCHEMBL30839288 | 0.90 | HTR2C (0.61) | HTR2CPRMT5MTNR1AMTNR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586171-A | Indole derivative, pharmaceutical composition and application thereof in central nervous field | 长春金赛药业有限责任公司 | 2024-02-23 | — | — | CN | disclosed |