Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.55 |
| ▸ | ATM | Q13315 | 5/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839662 | 0.85 | ATM (0.48) | ATMATR | |
| SCHEMBL30011979 | 0.75 | ATM (0.63) | KCNH2ATMATR | |
| SCHEMBL1999778 | 0.71 | HRH3 (1.00) | KCNH2HRH3ADRA1A | |
| SCHEMBL2003640 | 0.70 | HRH3 (1.00) | KCNH2HRH3ADRA1A | |
| SCHEMBL2004603 | 0.69 | HRH3 (1.00) | KCNH2HRH3ADRA1A | |
| SCHEMBL18641856 | 0.68 | ATM (0.61) | KCNH2ATMATR | |
| SCHEMBL2002500 | 0.68 | HRH3 (1.00) | KCNH2HRH3ADRA1A | |
| SCHEMBL2003152 | 0.68 | HRH3 (1.00) | KCNH2HRH3ADRA1A | |
| SCHEMBL2005370 | 0.67 | HRH3 (1.00) | KCNH2HRH3ADRA1A | |
| SCHEMBL18631950 | 0.67 | ATM (0.78) | KCNH2ATMATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026097-B | Substituted pyrazoloquinazolinone compounds and uses thereof | 上海瑛派药业有限公司 | 2024-02-23 | — | — | CN | disclosed |