Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842291 | 0.81 | CA12 (0.56) | CA12CA3CA4CA6CA5A | |
| SCHEMBL21857984 | 0.76 | CA9 (0.42) | CA12CA3CA4CA6CA5A | |
| SCHEMBL10696913 | 0.72 | POLB (0.50) | ALDH1A1TSHRHSD17B10MAPTMEN1 | |
| SCHEMBL9771587 | 0.71 | KAT2B (0.63) | CA12CA3CA4CA6CA5A | |
| Hydrochloric Acid SCHEMBL9771636 | 0.70 | KAT2B (0.66) | CA12CA3CA4CA6CA5A | |
| SCHEMBL5355772 | 0.69 | MAPT (0.61) | ALDH1A1RECQLHSD17B10MAPTMEN1 | |
| SCHEMBL29211172 | 0.68 | MYC (0.49) | CA12CA9CA14ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL515052 | 0.68 | MAPT (0.59) | ALDH1A1RECQLHSD17B10MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL28432645 | 0.68 | MAPT (0.59) | ALDH1A1RECQLHSD17B10MAPTMEN1 | |
| Nitric Acid SCHEMBL27877120 | 0.67 | CA12 (0.76) | CA12CA3CA4CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11952328-B2 | Selective ship inhibitors for treating disease | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2024-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11952328-B2 | Selective ship inhibitors for treating disease | PPM1A, MTMR1, PPM1B | CA12 4812/4885CA3 4859/4885CA4 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.