SCHEMBL30844931

SCHEMBL30844931

CCc1nc(CN2CCN(c3cc(C(F)(F)F)c4scc(C(=O)NC)c4n3)CC2)cs1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ UGT8 Q16880 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21813582 1.00 UGT8 (0.70) UGT8
SCHEMBL21814090 0.89 UGT8 (0.69) UGT8
SCHEMBL21813373 0.87 UGT8 (0.71) UGT8
SCHEMBL21814001 0.85 UGT8 (0.68) UGT8
SCHEMBL21813380 0.85 UGT8 (0.70) UGT8
SCHEMBL21813936 0.85 UGT8 (0.68) UGT8
SCHEMBL21814131 0.85 UGT8 (0.68) UGT8
SCHEMBL21813588 0.85 UGT8 (0.68) UGT8
SCHEMBL30845030 0.85 UGT8 (0.68) UGT8
SCHEMBL21813544 0.84 UGT8 (0.72) UGT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113423711-B Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof 建新公司 2024-03-15 — — CN claimed
CN-113423711-B Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof 建新公司 2024-03-15 — — CN disclosed
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